C.H. Arrowsmith

Princess Margaret Cancer Centre (CA)

Research Areas

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H-index

111

Publications

2918

Citations

42706

i10-index

385

Publications & Citations Over Time

Top Cited Publications

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Title	Year	Citations
Histone Recognition and Large-Scale Structural Ana...	2012	1697
Epigenetic protein families: a new frontier for dr...	2012	1288
Consistent blind protein structure generation from...	2008	848
The promise and peril of chemical probes	2015	828
Ductal pancreatic cancer modeling and drug screeni...	2015	733
Somatic mutations at EZH2 Y641 act dominantly thro...	2010	589
Chemical screening methods to identify ligands tha...	2006	588
Global analysis of protein folding using massively...	2017	533
Self-renewal as a therapeutic target in human colo...	2013	530
A chemical probe selectively inhibits G9a and GLP ...	2011	525

Publications

1.
Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family
Year: 2012Citations: 1697DOI: 10.1016/j.cell.2012.02.013
2.
Epigenetic protein families: a new frontier for drug discovery
Year: 2012Citations: 1288DOI: 10.1038/nrd3674
3.
Consistent blind protein structure generation from NMR chemical shift data
Year: 2008Citations: 848DOI: 10.1073/pnas.0800256105
4.
The promise and peril of chemical probes
Year: 2015Citations: 828DOI: 10.1038/nchembio.1867
5.
Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell– and patient-derived tumor organoids
Year: 2015Citations: 733DOI: 10.1038/nm.3973
6.
Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation
Year: 2010Citations: 589DOI: 10.1182/blood-2010-11-321208
7.
Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determination
Year: 2006Citations: 588DOI: 10.1073/pnas.0605224103
8.
Global analysis of protein folding using massively parallel design, synthesis, and testing
Year: 2017Citations: 533DOI: 10.1126/science.aan0693
9.
Self-renewal as a therapeutic target in human colorectal cancer
Year: 2013Citations: 530DOI: 10.1038/nm.3418
10.
A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells
Year: 2011Citations: 525DOI: 10.1038/nchembio.599

About C.H. Arrowsmith

C.H. Arrowsmith is a researcher with 2918 publications and 42706 citations. They are affiliated with Princess Margaret Cancer Centre. Their research focuses on . With an h-index of 111, they are among the top researchers in their field.

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Distribution of citations across publications

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Impact Metrics Over Time

Citations per publication by year